2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-A0019R
    Paliperidone (Standard)
    Paliperidone (Standard) is the analytical standard of Paliperidone. This product is intended for research and analytical applications. Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia.
    Paliperidone (Standard)
  • HY-118714
    α-Hydroxy alprazolam
    α-Hydroxy alprazolam (U 40125) is a main metabolite of Alprazolam. α-Hydroxy alprazolam is pharmacologically active accounting for 60% of the activity of Alprazolam.
    α-Hydroxy alprazolam
  • HY-W353470
    2,3-Dinor-8-iso prostaglandin F 2α
    2,3-Dinor-8-iso prostaglandin F₂α (2,3-Dinor-8-isoPGF2α) is the major β-oxidation metabolite of 8-iso-prostaglandin F₂α. 2,3-Dinor-8-iso prostaglandin F₂α serves as a biomarker to evaluate the in vivo production of 8-iso-prostaglandin F₂α and the level of lipid peroxidation. 2,3-Dinor-8-iso prostaglandin F₂α is promising for research of oxidative stress-related diseases such as arteriosclerosis and diabetes.
    2,3-Dinor-8-iso prostaglandin F 2α
  • HY-153995A
    D-Ribonic acid
    D-Ribonic acid is a metabolite derived from D-Ribose (HY-113375). D-Ribonic acid may be involved in the mitochondrial energy production process.
    D-Ribonic acid
  • HY-169039
    Δ9-THCQ
    Δ9-THCQ (Δ9-Tetrahydrocannabinoquinone) is an oxidative byproduct of Δ9-THC.
    Δ9-THCQ
  • HY-W653885
    rac 3,4-Dihydroxymandelic Acid-d3
    rac 3,4-Dihydroxymandelic Acid-d3 is deuterium labeled 3,4-Dihydroxymandelic acid. 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.
    rac 3,4-Dihydroxymandelic Acid-</sub>d<sub>3</sub>
  • HY-N15317
    Phocaecholic acid
    		≥98.0%
    Phocaecholic acid (β-Phocaecholic acid) is a bile acid found in duck bile. Phocaecholic acid can be excreted into bile and partially decarboxylated to nor-chenodeoxycholic acid in rats. Phocaecholic acid is promising for research of bile acid metabolism and related diseases.
    Phocaecholic acid
  • HY-W031110
    2-Methyl-tetrahydro-β-carboline
    2-Methyl-tetrahydro-β-carboline is a cyclization product of N,N-dimethyltryptamine after oral administration of ayahuasca.
    2-Methyl-tetrahydro-β-carboline
  • HY-N8067
    Terbufoxon sulfoxide
    Terbufoxon sulfoxide (Terbufos oxon sulfoxide) is a metabolite of the insecticide Terbufos in the pepper leaf matrix.
    Terbufoxon sulfoxide
  • HY-G0010S
    N-desmethyl Netupitant-d6
    N-desmethyl Netupitant-d6 is the deuterium labeled N-desmethyl Netupitant, which is a metabolite of Netupitant.
    N-desmethyl Netupitant-d<sub>6</sub>
  • HY-W016034R
    Acetaminophen glucuronide sodium salt (Standard)
    Acetaminophen glucuronide (sodium salt) (Standard) is the analytical standard of Acetaminophen glucuronide (sodium salt). This product is intended for research and analytical applications. Acetaminophen glucuronide is a safe and effective antipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liver and kidney .
    Acetaminophen glucuronide sodium salt (Standard)
  • HY-131637R
    Desacetyl bisacodyl (Standard)
    Desacetyl bisacodyl (Standard) is the analytical standard of Desacetyl bisacodyl. This product is intended for research and analytical applications. Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion.
    Desacetyl bisacodyl (Standard)
  • HY-135731AR
    4-Methylamino antipyrine hydrochloride (Standard)
    4-Methylamino antipyrine (hydrochloride) (Standard) is the analytical standard of 4-Methylamino antipyrine (hydrochloride). This product is intended for research and analytical applications. 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties.
    4-Methylamino antipyrine hydrochloride (Standard)
  • HY-135397R
    (R)-?Linezolid (Standard)
    (R)-​Linezolid (Standard) is the analytical standard of (R)-​Linezolid. This product is intended for research and analytical applications. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis.
    (R)-?Linezolid (Standard)
  • HY-137575
    Terbutalone
    Terbutalone is a derivative of Terbutaline (HY-B0802A). Terbutaline is an orally active β2-adrenergic receptor agonist and an active metabolite of Bambuterol (HY-17501). Terbutaline can be used in asthma symptom research.
    Terbutalone
  • HY-137389
    Anhydro abiraterone
    Anhydro abiraterone is a degradation product of Abiraterone acetate (HY-75054). Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity.
    Anhydro abiraterone
  • HY-133925
    6-O-Desmethyl donepezil
    6-O-Desmethyl donepezil is the metabolite of Donepezil (HY-14566). 6-O-Desmethyl donepezil is an inhibitor for hERG channel with an IC50 of 1 μM.
    6-O-Desmethyl donepezil
  • HY-Y1771R
    2-Carboxybenzaldehyde (Standard)
    2-Carboxybenzaldehyde (Standard) is the analytical standard of 2-Carboxybenzaldehyde. This product is intended for research and analytical applications. 2-Carboxybenzaldehyde is the major metabolite found in phenanthrene metabolism. Phenanthrene can be degrade by Pseudomonas sp. Lphe-2 strain.
    2-Carboxybenzaldehyde (Standard)
  • HY-137393
    3α,5α-Tetrahydronorethisterone
    3α,5α-Tetrahydronorethisterone is the major urinary metabolites of Norethisterone (HY-B0554).
    3α,5α-Tetrahydronorethisterone
  • HY-120201
    7-Hydroxy coumarin glucuronide sodium
    7-Hydroxy coumarin glucuronide sodium is a benzopyrone and a metabolite of 7-hydroxy coumarin.
    7-Hydroxy coumarin glucuronide sodium
Cat. No. Product Name / Synonyms Application Reactivity